Resource Documents by Bucca, Giselda
Möller-Levet, Carla; Archer, Simon; Bucca, Giselda; et al.
Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome
Insufficient sleep and circadian rhythm disruption are associated with negative health outcomes, including obesity, cardiovascular disease, and cognitive impairment, but the mechanisms involved remain largely unexplored. Twenty-six participants were exposed to 1 wk of insufficient sleep (sleep-restriction condition 5.70 h, SEM = 0.03 sleep per 24 h) and 1 wk of sufficient sleep (control condition 8.50 h sleep, SEM = 0.11). Immediately following each condition, 10 whole-blood RNA samples were collected from each participant, while controlling for the effects of . . . Complete article »
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